KBTBD11-OT1

Across TCGA pan-cancer cohorts, KBTBD11-OT1 RNA is linked to patient survival in 23 of 34 cancer types, making it the most broadly survival-associated KBTBD11-OT1 data layer.

The strongest signal is observed in uterine corpus endometrial carcinoma (UCEC), where higher KBTBD11-OT1 RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated KBTBD11-OT1 expression acts as an unfavorable survival marker, although some lineages such as READ and LIHC show a favorable association.

UCEC, LUSC, and READ are the cancer types where KBTBD11-OT1 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
UCEC	DFS	Quartile	All	0.794	0.889	.006	72	view →
LUSC	DFS	Quartile	III,IV	0.325	0.729	<.001	51	view →
READ	OS	Median	All	0.855	0.454	.001	49	view →
LIHC	DFS	Median	III,IV	0.473	0.191	<.001	41	view →
GBM	OS	Quartile	All	0.275	0.504	.002	23	view →
LUAD	DFS	Tertile	III,IV	0.301	0.576	.016	22	view →
THCA	DFS	Quartile	All	0.838	0.951	.016	17	view →
UCS	DFS	Tertile	II,III,IV	0.695	0.287	.008	14	view →
MESO	OS	Tertile	IV	0.363	0.928	.013	12	view →
ESCA	DFS	Tertile	III,IV	0.344	0.568	.016	12	view →
BRCA	OS	Median	III,IV	0.939	0.864	.016	11	view →
STAD	DFS	Tertile	IV	0.163	0.554	.037	9	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 23 lineages.

KBTBD11-OT1–UCEC (DFS)

Open the UCEC breakdown →