KBTBD11-OT1

Across TCGA pan-cancer cohorts, KBTBD11-OT1 RNA differs between tumor and matched normal tissue in 10 of 18 cancer types tested, making tumor–normal expression one of KBTBD11-OT1’s most consistent transcriptional readouts.

The strongest signal is observed in kidney chromophobe (KICH), where KBTBD11-OT1 RNA is repressed in tumor relative to normal tissue. In most cancer types KBTBD11-OT1 is over-expressed in tumor, although a few such as KICH and COAD show the opposite, repressed pattern.

KICH, COAD, and LIHC are the cancer types where KBTBD11-OT1 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in KBTBD11-OT1 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
KICH	Male	All	−1.688	<.001	11	view →
COAD	Female	II,III,IV	−1.246	<.001	11	view →
LIHC	All	II,III,IV	−0.404	<.001	8	view →
READ	All	All	−1.020	<.001	5	view →
KIRC	All	All	+0.338	.001	5	view →
THCA	All	All	−0.176	<.001	4	view →
CHOL	All	All	−0.295	.001	3	view →
LUSC	All	All	−0.175	.015	3	view →
BRCA	Female	All	−0.076	.040	2	view →
KIRP	All	II,III,IV	+0.408	.041	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 10 strongest of 10 lineages.

KBTBD11-OT1–KICH

Open the KICH breakdown →