Across TCGA patient cohorts, KAZN protein abundance is significantly associated with the RNA expression of many other genes, with 5,695 significant associations in total. CCRCC shows the largest number of these associations.

The most reproducible KAZN-associated genes across cancer lineages are ALDH4A1, LZIC, and MBNL1-AS1. Each is linked with KAZN in more than 2 cancer types. Because this analysis shows association rather than direction, both KAZN-to-partner and partner-to-KAZN results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (KAZN→partner) and Y-score (partner→KAZN) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	ALDH4A1 →	+0.677	+0.306	<.001	<.001	3	3
OV	LZIC →	+0.422	+0.423	.002	.005	3	3
LSCC	MBNL1-AS1 →	-0.484	-0.317	<.001	<.001	3	3
UCEC	ZC3HAV1 →	-0.471	-0.484	<.001	<.001	3	3
GBM	PRKN →	+0.447	+0.427	<.001	<.001	3	3
HNSC	CD5 →	-0.702	-0.317	<.001	.002	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,695 associations by consensus.

Exploration

KAZN survival (RNA) · tumor vs normal (RNA) · all KAZN data types