Across TCGA pan-cancer cohorts, KAZN RNA is linked to patient survival in 25 of 34 cancer types, making it the most broadly survival-associated KAZN data layer compared with 4 for mutation status and 5 for mass-spec protein.
The strongest signal is observed in kidney renal papillary cell carcinoma (KIRP), where higher KAZN RNA is associated with better overall survival. In most high-consensus cancer types, elevated KAZN expression acts as an unfavorable survival marker, although some lineages such as KIRP and HNSC show a favorable association.
KIRP, HNSC, and ACC are the cancer types where KAZN RNA most reproducibly stratifies survival.
RNA survival associations by lineage
Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.