KAZALD1

Across TCGA patient cohorts, KAZALD1 mutation is significantly associated with the RNA expression of many other genes, with 260 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible KAZALD1-associated genes across cancer lineages are TOMM22P5, FUNDC2P3, and RNU1-91P. Each is linked with KAZALD1 in more than 2 cancer types. Because this analysis shows association rather than direction, both KAZALD1-to-partner and partner-to-KAZALD1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, TOMM22P5 grouped by KAZALD1-low versus KAZALD1-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (KAZALD1→partner) and Y-score (partner→KAZALD1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	TOMM22P5 →	+0.270	+4.424	.001	<.001	3	3
LUSC	FUNDC2P3 →	+0.120	+5.093	.003	.008	3	2
SKCM	RNU1-91P →	+0.311	+3.045	<.001	.008	3	2
UCEC	RNU6-181P →	+0.826	+3.028	<.001	.002	3	2
UCEC	RNU6-741P →	+0.463	+4.245	<.001	.006	3	2
UCEC	ACD →	+0.970	+3.191	<.001	.009	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 260 associations by consensus.

TOMM22P5 by KAZALD1 expression — UCEC

Explore this box plot interactively →