KAT8

Across TCGA patient cohorts, KAT8 protein abundance is significantly associated with the RNA expression of many other genes, with 19,514 significant associations in total. GBM shows the largest number of these associations.

The most reproducible KAT8-associated genes across cancer lineages are TMEM97, NTHL1, and CIAO3. Each is linked with KAT8 in more than 5 cancer types. Because this analysis shows association rather than direction, both KAT8-to-partner and partner-to-KAT8 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, KAT8 versus TMEM97 in LSCC, with a Pearson correlation of 0.52.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (KAT8→partner) and Y-score (partner→KAT8) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	TMEM97 →	+1.398	+0.358	<.001	<.001	3	6
UCEC	NTHL1 →	+1.164	+0.232	.003	<.001	2	6
BRCA	CIAO3 →	+0.513	+0.242	.004	.003	3	5
LSCC	MAZ →	+0.743	+0.372	<.001	<.001	3	5
OV	CLEC2B →	-0.832	-0.274	.004	<.001	3	5
HNSC	ALDH5A1 →	+0.821	+0.232	<.001	.002	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 19,514 associations by consensus.

KAT8 vs TMEM97 — LSCC

Explore this scatter interactively →