KAT8

Across TCGA patient cohorts, KAT8 protein abundance is significantly associated with the protein abundance of many other proteins, with 33,073 significant associations in total. GBM shows the largest number of these associations.

The most reproducible KAT8-associated proteins across cancer lineages are ASH2L, SIN3A, and YY1. Each is linked with KAT8 in more than 8 cancer types. Because this analysis shows association rather than direction, both KAT8-to-partner and partner-to-KAT8 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, KAT8 versus ASH2L in GBM, with a Pearson correlation of 0.70.

protein abundance associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (KAT8→partner) and Y-score (partner→KAT8) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	ASH2L →	+0.345	+0.280	<.001	<.001	3	9
GBM	SIN3A →	+0.341	+0.270	<.001	<.001	3	9
COAD	YY1 →	+0.405	+0.287	.001	.007	3	9
OV	CXXC1 →	+0.331	+0.348	<.001	<.001	3	9
GBM	HCFC1 →	+0.300	+0.294	<.001	<.001	3	8
OV	HIRIP3 →	+0.496	+0.281	<.001	<.001	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 33,073 associations by consensus.

KAT8 vs ASH2L — GBM

Explore this scatter interactively →