KAT2A

Across TCGA patient cohorts, KAT2A protein abundance is significantly associated with the RNA expression of many other genes, with 15,131 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible KAT2A-associated genes across cancer lineages are CENPL, SNHG29, and FANCE. Each is linked with KAT2A in more than 4 cancer types. Because this analysis shows association rather than direction, both KAT2A-to-partner and partner-to-KAT2A results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, KAT2A versus CENPL in LSCC, with a Pearson correlation of 0.43.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (KAT2A→partner) and Y-score (partner→KAT2A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	CENPL →	+0.696	+0.413	<.001	<.001	3	5
OV	SNHG29 →	+0.858	+0.466	.008	.005	3	4
BRCA	FANCE →	+0.767	+0.258	<.001	<.001	3	4
LSCC	POLR1B →	+0.520	+0.314	<.001	<.001	3	4
BRCA	WDR74 →	+0.440	+0.224	<.001	<.001	3	4
LSCC	PSRC1 →	+0.837	+0.345	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 15,131 associations by consensus.

KAT2A vs CENPL — LSCC

Explore this scatter interactively →