KANSL3

Across TCGA cell cohorts, KANSL3 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,761 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible KANSL3-associated GO terms across cancer lineages are Positive regulation of organelle assembly, Positive regulation of double-strand break repair, and Heterochromatin organization. Each is linked with KANSL3 in more than 17 cancer types. Because this analysis shows association rather than direction, both KANSL3-to-partner and partner-to-KANSL3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of organelle assembly grouped by KANSL3-low versus KANSL3-high in UPPER_AERODIGESTIVE_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (KANSL3→partner) and Y-score (partner→KANSL3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UPPER_AERODIGESTIVE_TRACT	Positive regulation of organelle assembly →	+0.073	+0.893	<.001	<.001	3	18
BONE	Positive regulation of double-strand break repair →	+0.085	+0.749	<.001	<.001	3	18
BONE	Heterochromatin organization →	+0.074	+0.695	<.001	<.001	3	17
OESOPHAGUS	Negative regulation of syncytium formation by plasma membrane fusion →	+0.148	+0.908	<.001	<.001	3	17
BONE	Positive regulation of DNA repair →	+0.078	+0.766	<.001	<.001	3	16
OESOPHAGUS	Negative regulation of myoblast fusion →	+0.149	+0.854	<.001	<.001	3	16

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,761 associations by consensus.

Positive regulation of organelle assembly by KANSL3 expression — UPPER_AERODIGESTIVE_TRACT

Explore this box plot interactively →