KANSL3

Across TCGA cell cohorts, KANSL3 mutation is significantly associated with the RNA expression of many other genes, with 15 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible KANSL3-associated genes across cancer lineages are KRTAP19-3, SLC6A18, and CEACAM3. Each is linked with KANSL3 in more than 1 cancer types. Because this analysis shows association rather than direction, both KANSL3-to-partner and partner-to-KANSL3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, KRTAP19-3 grouped by KANSL3-low versus KANSL3-high in LUNG_SCLC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (KANSL3→partner) and Y-score (partner→KANSL3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_SCLC	KRTAP19-3 →	+0.241	+5.029	<.001	.006	3	1
BLOOD_Lymphoma	SLC6A18 →	+0.031	+3.192	<.001	.008	3	1
BLOOD_Lymphoma	CEACAM3 →	+0.100	+3.342	<.001	.008	3	1
SKIN	GGTLC2 →	+0.032	+3.688	<.001	.002	3	1
SKIN	APOL5 →	+0.070	+3.345	<.001	.007	3	1
SKIN	OR2AP1 →	+0.008	+4.022	<.001	.006	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 15 associations by consensus.

KRTAP19-3 by KANSL3 expression — LUNG_SCLC

Explore this box plot interactively →