KANSL2

Across TCGA patient cohorts, KANSL2 protein abundance is significantly associated with the RNA expression of many other genes, with 10,597 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible KANSL2-associated genes across cancer lineages are FANCB, POLA1, and SOD2. Each is linked with KANSL2 in more than 3 cancer types. Because this analysis shows association rather than direction, both KANSL2-to-partner and partner-to-KANSL2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, KANSL2 versus FANCB in OV, with a Pearson correlation of 0.51.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (KANSL2→partner) and Y-score (partner→KANSL2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	FANCB →	+0.609	+0.520	.007	.001	3	4
LSCC	POLA1 →	+0.736	+0.281	<.001	<.001	3	4
GBM	SOD2 →	-0.917	-0.222	<.001	.008	3	4
OV	MCM3 →	+1.069	+0.657	.008	.002	3	3
LSCC	RBM19 →	+0.656	+0.196	.007	.005	3	3
OV	LMNB2 →	+0.795	+0.689	.008	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 10,597 associations by consensus.

KANSL2 vs FANCB — OV

Explore this scatter interactively →