KANSL2

Across TCGA cell cohorts, KANSL2 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,362 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible KANSL2-associated GO terms across cancer lineages are Regulation of DNA repair, Recombinational repair, and DNA strand elongation involved in DNA replication. Each is linked with KANSL2 in more than 12 cancer types. Because this analysis shows association rather than direction, both KANSL2-to-partner and partner-to-KANSL2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of DNA repair grouped by KANSL2-low versus KANSL2-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (KANSL2→partner) and Y-score (partner→KANSL2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Regulation of DNA repair →	+0.060	+0.551	<.001	<.001	3	13
BONE	Recombinational repair →	+0.113	+0.721	<.001	<.001	3	13
UPPER_AERODIGESTIVE_TRACT	DNA strand elongation involved in DNA replication →	+0.151	+1.021	.004	<.001	3	13
BONE	Heterochromatin formation →	+0.076	+0.579	.003	.006	3	12
BONE	Regulation of centrosome duplication →	+0.097	+0.573	.002	.009	2	13
LUNG_NSCLC_LUSC	Chromosomal 5-methylcytosine DNA demethylation pathway →	+0.222	+0.901	<.001	.002	3	12

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,362 associations by consensus.

Regulation of DNA repair by KANSL2 expression — BONE

Explore this box plot interactively →