KANSL1L

Across TCGA patient cohorts, KANSL1L mutation is significantly associated with the RNA expression of many other genes, with 3,825 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible KANSL1L-associated genes across cancer lineages are GPC6-AS1, FXYD6P2, and CDH12P2. Each is linked with KANSL1L in more than 1 cancer types. Because this analysis shows association rather than direction, both KANSL1L-to-partner and partner-to-KANSL1L results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, GPC6-AS1 grouped by KANSL1L-low versus KANSL1L-high in CESC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (KANSL1L→partner) and Y-score (partner→KANSL1L) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CESC	GPC6-AS1 →	+0.129	+5.539	<.001	.004	3	2
LUAD	FXYD6P2 →	+0.193	+3.651	<.001	.002	3	2
LUAD	CDH12P2 →	+0.101	+5.011	<.001	.002	3	2
COAD	ACTR3BP5 →	+0.029	+5.149	.008	.001	3	2
COAD	FTLP18 →	+0.088	+5.149	<.001	.001	3	2
COAD	IFNA11P →	+0.175	+4.266	<.001	.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,825 associations by consensus.

GPC6-AS1 by KANSL1L expression — CESC

Explore this box plot interactively →