KANSL1L

Across TCGA pan-cancer cohorts, KANSL1L RNA differs between tumor and matched normal tissue in 12 of 18 cancer types tested, making tumor–normal expression one of KANSL1L’s most consistent transcriptional readouts.

The strongest signal is observed in kidney chromophobe (KICH), where KANSL1L RNA is repressed in tumor relative to normal tissue. In most cancer types KANSL1L is over-expressed in tumor, although a few such as KICH and LUSC show the opposite, repressed pattern.

KICH, LUSC, and UCEC are the cancer types where KANSL1L tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in KANSL1L RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
KICH	Female	II,III,IV	−1.881	<.001	11	view →
LUSC	All	III,IV	−1.176	<.001	9	view →
UCEC	All	All	−0.932	<.001	8	view →
THCA	All	II,III,IV	−0.601	<.001	7	view →
KIRP	All	II,III,IV	+0.707	.007	6	view →
BRCA	All	III,IV	−0.691	<.001	6	view →
LUAD	All	III,IV	−0.674	<.001	6	view →
COAD	Male	All	+0.557	<.001	6	view →
BLCA	Male	All	−0.648	.016	4	view →
LIHC	All	All	+0.440	<.001	4	view →
CHOL	All	All	+2.193	<.001	3	view →
KIRC	All	All	+0.239	.024	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 12 strongest of 12 lineages.

KANSL1L–KICH

Open the KICH breakdown →