KANSL1L

Across TCGA cell cohorts, KANSL1L mutation is significantly associated with the RNA expression of many other genes, with 515 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible KANSL1L-associated genes across cancer lineages are PLPP5, OR2D3, and OR10K2. Each is linked with KANSL1L in more than 1 cancer types. Because this analysis shows association rather than direction, both KANSL1L-to-partner and partner-to-KANSL1L results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, PLPP5 grouped by KANSL1L-low versus KANSL1L-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (KANSL1L→partner) and Y-score (partner→KANSL1L) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	PLPP5 →	+0.565	+2.043	.009	.008	3	2
LARGE_INTESTINE	OR2D3 →	+0.016	+1.925	<.001	.006	3	2
BREAST	OR10K2 →	+0.038	+4.196	<.001	.006	3	1
BREAST	OR10T2 →	+0.110	+4.196	<.001	.006	3	1
STOMACH	SSX7 →	+0.325	+4.285	<.001	.007	3	1
LARGE_INTESTINE	TOP3B →	+0.590	+2.043	.009	.008	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 515 associations by consensus.

PLPP5 by KANSL1L expression — LARGE_INTESTINE

Explore this box plot interactively →