Across TCGA pan-cancer cohorts, KANSL1-AS1 RNA differs between tumor and matched normal tissue in 4 of 18 cancer types tested, making tumor–normal expression one of KANSL1-AS1’s most consistent transcriptional readouts.

The strongest signal is observed in kidney chromophobe (KICH), where KANSL1-AS1 RNA is repressed in tumor relative to normal tissue. In most cancer types KANSL1-AS1 is over-expressed in tumor, although a few such as KICH and BRCA show the opposite, repressed pattern.

KICH, BRCA, and LUAD are the cancer types where KANSL1-AS1 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in KANSL1-AS1 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
KICH	All	All	−1.166	<.001	6	view →
BRCA	All	All	−0.375	.004	4	view →
LUAD	Male	III,IV	−0.753	.012	2	view →
BLCA	Male	IV	−0.864	.014	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 4 strongest of 4 lineages.

Exploration

Same gene, other analysis: KANSL1-AS1 RNA expression & survival · all KANSL1-AS1 data types