KANK3

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, KANK3 mutation is significantly associated with the RNA expression of many other genes, with 820 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible KANK3-associated genes across cancer lineages are C9orf62, OR10C1, and TRAJ61. Each is linked with KANK3 in more than 1 cancer types. Because this analysis shows association rather than direction, both KANK3-to-partner and partner-to-KANK3 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (KANK3→partner) and Y-score (partner→KANK3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
UCECC9orf62 →+0.086+2.719<.001.00632
HNSCOR10C1 →+0.049+7.132<.001<.00132
HNSCTRAJ61 →+1.254+5.182<.001.00732
HNSCMTND6P1 →+0.106+8.366<.001<.00132
CESCPIEZO1P2 →+0.020+3.816.001.00732
SKCMRNU7-61P →+0.705+4.683<.001.00132
Each partner links to its Q-omics profile. Showing the 6 strongest of 820 associations by consensus.

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