Across TCGA cell cohorts, KANK3 mutation is significantly associated with the RNA expression of many other genes, with 13 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible KANK3-associated genes across cancer lineages are GCM2, OR13D1, and ELOA3CP. Each is linked with KANK3 in more than 1 cancer types. Because this analysis shows association rather than direction, both KANK3-to-partner and partner-to-KANK3 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (KANK3→partner) and Y-score (partner→KANK3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	GCM2 →	+0.072	+4.242	<.001	.001	3	1
LARGE_INTESTINE	OR13D1 →	+0.026	+3.882	<.001	.001	3	1
LARGE_INTESTINE	ELOA3CP →	+0.163	+3.509	<.001	.008	3	1
LUNG_NSCLC_LUAD	MS4A6E →	+0.044	+5.228	<.001	.005	3	1
LUNG_NSCLC_LUAD	C16orf82 →	+0.013	+5.662	<.001	.002	3	1
LUNG_NSCLC_LUAD	KRTAP10-11 →	+0.018	+4.887	<.001	.009	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 13 associations by consensus.

Exploration

KANK3 survival (RNA) · tumor vs normal (RNA) · all KANK3 data types