KALRN

Across TCGA patient cohorts, KALRN protein abundance is significantly associated with the RNA expression of many other genes, with 7,743 significant associations in total. PDAC shows the largest number of these associations.

The most reproducible KALRN-associated genes across cancer lineages are VSIG2, PLPPR4, and CACNA1C. Each is linked with KALRN in more than 4 cancer types. Because this analysis shows association rather than direction, both KALRN-to-partner and partner-to-KALRN results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, KALRN versus VSIG2 in PDAC, with a Pearson correlation of 0.41.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (KALRN→partner) and Y-score (partner→KALRN) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PDAC	VSIG2 →	+1.721	+0.508	<.001	<.001	3	5
GBM	PLPPR4 →	+0.967	+0.293	<.001	<.001	3	4
UCEC	CACNA1C →	+0.876	+0.383	<.001	<.001	3	4
CCRCC	ROBO4 →	+0.991	+0.437	.001	<.001	3	4
UCEC	DACT3 →	+0.888	+0.398	<.001	<.001	3	4
CCRCC	IRAG1 →	+1.021	+0.474	.005	.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,743 associations by consensus.

KALRN vs VSIG2 — PDAC

Explore this scatter interactively →