KALRN

RNA expression — cross-omics
Cross-omicsRNA → FUNCTION-RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, KALRN RNA expression is significantly associated with the go_rna of many other GO terms, with 5,251 significant associations in total. CNS shows the largest number of these associations.

The most reproducible KALRN-associated GO terms across cancer lineages are Chondroblast differentiation, ATP biosynthetic process, and Golgi to endosome transport. Each is linked with KALRN in more than 9 cancer types. Because this analysis shows association rather than direction, both KALRN-to-partner and partner-to-KALRN results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Chondroblast differentiation grouped by KALRN-low versus KALRN-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (KALRN→partner) and Y-score (partner→KALRN) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner GO termX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
BONEChondroblast differentiation →-0.815-1.080.007.006310
SKINATP biosynthetic process →+0.096+1.482<.001<.001310
BREASTGolgi to endosome transport →+0.098+1.231<.001.003310
UPPER_AERODIGESTIVE_TRACTPositive regulation of viral process →+0.076+0.971.001.00239
OVARYOxidative phosphorylation →+0.086+1.316<.001<.00139
SKINMitochondrial electron transport, NADH to ubiquinone →+0.095+1.684<.001<.00139
Each partner links to its Q-omics profile. Showing the 6 strongest of 5,251 associations by consensus.

Chondroblast differentiation by KALRN expression — BONE

Box plot of Chondroblast differentiation in KALRN-low vs KALRN-high samples in BONE.

Explore this box plot interactively →

Exploration