KAAG1

Across TCGA patient cohorts, KAAG1 mutation is significantly associated with the RNA expression of many other genes, with 9 significant associations in total. SKCM shows the largest number of these associations.

The most reproducible KAAG1-associated genes across cancer lineages are LINC01381, OR7E149P, and SPINK14. Each is linked with KAAG1 in more than 1 cancer types. Because this analysis shows association rather than direction, both KAAG1-to-partner and partner-to-KAAG1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, LINC01381 grouped by KAAG1-low versus KAAG1-high in COAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (KAAG1→partner) and Y-score (partner→KAAG1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	LINC01381 →	+0.199	+5.080	<.001	.008	3	1
SKCM	OR7E149P →	+0.042	+5.080	<.001	.004	3	1
SKCM	SPINK14 →	+0.145	+4.771	<.001	.006	3	1
SKCM	RNU6-234P →	+0.451	+4.771	<.001	.006	3	1
SKCM	RNU6-1067P →	+0.414	+4.500	.003	.005	3	1
SKCM	MIR34B →	+0.307	+4.594	<.001	.008	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 9 associations by consensus.

LINC01381 by KAAG1 expression — COAD

Explore this box plot interactively →