JUND

mutation — cross-omics
Cross-omicsMUTATION → IMMUNEPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, JUND mutation is significantly associated with the immune_cell of many other genes, with 3 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible JUND-associated genes across cancer lineages are Platelets, Mast cells, and mv Endothelial cells. Each is linked with JUND in more than 1 cancer types. Because this analysis shows association rather than direction, both JUND-to-partner and partner-to-JUND results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Platelets grouped by JUND-low versus JUND-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (JUND→partner) and Y-score (partner→JUND) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
UCECPlatelets →+0.031+2.470<.001.01231
UCECMast cells →+0.033+3.042<.001.01811
UCECmv Endothelial cells →-0.027-2.989.049.03711
Each partner links to its Q-omics profile. Showing the 3 strongest of 3 associations by consensus.

Platelets by JUND expression — UCEC

Box plot of Platelets in JUND-low vs JUND-high samples in UCEC.

Explore this box plot interactively →

Exploration