JUND

Across TCGA pan-cancer cohorts, JUND RNA differs between tumor and matched normal tissue in 9 of 18 cancer types tested, making tumor–normal expression one of JUND’s most consistent transcriptional readouts.

The strongest signal is observed in bladder urothelial carcinoma (BLCA), where JUND RNA is repressed in tumor relative to normal tissue. In most cancer types JUND is over-expressed in tumor, although a few such as BLCA and LUAD show the opposite, repressed pattern.

BLCA, LUAD, and LUSC are the cancer types where JUND tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in JUND RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
BLCA	All	All	−1.382	<.001	12	view →
LUAD	Male	All	−1.674	<.001	11	view →
LUSC	Male	II,III,IV	−1.616	<.001	8	view →
KICH	Male	All	−0.999	<.001	7	view →
UCEC	All	III,IV	−1.264	<.001	6	view →
BRCA	All	III,IV	−0.818	<.001	6	view →
KIRC	All	II,III,IV	−0.439	.002	6	view →
THCA	Female	All	−0.857	<.001	4	view →
HNSC	Female	IV	−1.048	.004	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 9 strongest of 9 lineages.

JUND–BLCA

Open the BLCA breakdown →