JUND

Across TCGA cell cohorts, JUND mutation is significantly associated with the RNA expression of many other genes, with 14 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible JUND-associated genes across cancer lineages are MYMK, TRIM64B, and MTRNR2L10. Each is linked with JUND in more than 1 cancer types. Because this analysis shows association rather than direction, both JUND-to-partner and partner-to-JUND results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MYMK grouped by JUND-low versus JUND-high in UPPER_AERODIGESTIVE_TRACT.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (JUND→partner) and Y-score (partner→JUND) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UPPER_AERODIGESTIVE_TRACT	MYMK →	+0.030	+4.510	<.001	.003	3	1
UPPER_AERODIGESTIVE_TRACT	TRIM64B →	+0.014	+4.870	<.001	.001	3	1
UPPER_AERODIGESTIVE_TRACT	MTRNR2L10 →	+0.096	+4.209	.004	.006	3	1
BLOOD_Leukemia	TCF21 →	+0.011	+4.705	<.001	.003	3	1
BLOOD_Leukemia	OR10V1 →	+0.035	+5.569	<.001	.001	3	1
BLOOD_Leukemia	HTR3D →	+0.014	+4.539	<.001	.007	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 14 associations by consensus.

MYMK by JUND expression — UPPER_AERODIGESTIVE_TRACT

Explore this box plot interactively →