JUNB

Across TCGA pan-cancer cohorts, JUNB mass-spec protein is linked to patient survival in 6 of 34 cancer types, making it a survival-associated JUNB data layer compared with 25 for mass-spec protein and 1 for mutation status.

The strongest signal is observed in head and neck squamous cell carcinoma (HNSC), where higher JUNB mass-spec protein is associated with worse disease-free survival. In most high-consensus cancer types, elevated JUNB expression acts as an unfavorable survival marker, although some lineages such as UCEC and GBM show a favorable association.

HNSC, CCRCC, and LUAD are the cancer types where JUNB mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
HNSC	DFS	Median	IV	0.632	0.902	.004	37	view →
CCRCC	DFS	Median	II,III,IV	0.451	1.000	.008	20	view →
LUAD	OS	Quartile	II,III,IV	0.435	0.939	.002	19	view →
PDAC	OS	Quartile	II,III,IV	0.421	0.701	.014	4	view →
UCEC	OS	Quartile	II,III,IV	1.000	0.373	.034	4	view →
GBM	OS	Median	All	0.903	0.633	.043	1	view →

Pink = unfavorable, green = favorable. Showing the 6 strongest of 6 lineages.

JUNB–HNSC (DFS)

Open the HNSC breakdown →