JUNB

Across TCGA patient cohorts, JUNB mutation is significantly associated with the RNA expression of many other genes, with 70 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible JUNB-associated genes across cancer lineages are BNIP3P4, RNA5SP367, and RNU6-179P. Each is linked with JUNB in more than 1 cancer types. Because this analysis shows association rather than direction, both JUNB-to-partner and partner-to-JUNB results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, BNIP3P4 grouped by JUNB-low versus JUNB-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (JUNB→partner) and Y-score (partner→JUNB) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	BNIP3P4 →	+0.143	+4.069	<.001	.002	3	2
BLCA	RNA5SP367 →	+0.687	+5.038	<.001	.009	3	2
BLCA	RNU6-179P →	+0.394	+6.444	<.001	.001	3	2
UCEC	ELOCP24 →	+0.134	+4.132	.004	.009	3	2
UCEC	NEK4P3 →	+0.109	+3.800	.009	.001	3	1
UCEC	VCX2 →	+0.231	+3.018	.009	.009	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 70 associations by consensus.

BNIP3P4 by JUNB expression — UCEC

Explore this box plot interactively →