JUNB

Across TCGA cell cohorts, JUNB mutation is significantly associated with the RNA expression of many other genes, with 59 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible JUNB-associated genes across cancer lineages are ZSWIM2, BARHL2, and UBE2U. Each is linked with JUNB in more than 1 cancer types. Because this analysis shows association rather than direction, both JUNB-to-partner and partner-to-JUNB results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, ZSWIM2 grouped by JUNB-low versus JUNB-high in OESOPHAGUS.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (JUNB→partner) and Y-score (partner→JUNB) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OESOPHAGUS	ZSWIM2 →	+0.128	+4.017	.002	.007	3	2
OESOPHAGUS	BARHL2 →	+0.047	+4.017	.005	.007	3	1
OESOPHAGUS	UBE2U →	+0.125	+4.017	.003	.007	3	1
OESOPHAGUS	PLA2G2C →	+0.056	+4.017	<.001	.007	3	1
OESOPHAGUS	APOC4 →	+0.104	+4.017	<.001	.007	3	1
OESOPHAGUS	AFM →	+0.011	+4.392	.003	.003	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 59 associations by consensus.

ZSWIM2 by JUNB expression — OESOPHAGUS

Explore this box plot interactively →