JUN

Across TCGA patient cohorts, JUN protein abundance is significantly associated with the RNA expression of many other genes, with 9,634 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible JUN-associated genes across cancer lineages are SLC2A1, RND3, and SEC23A. Each is linked with JUN in more than 6 cancer types. Because this analysis shows association rather than direction, both JUN-to-partner and partner-to-JUN results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, JUN versus SLC2A1 in HNSC, with a Pearson correlation of 0.39.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (JUN→partner) and Y-score (partner→JUN) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	SLC2A1 →	+1.124	+0.473	<.001	<.001	3	7
BRCA	RND3 →	+1.100	+0.480	<.001	<.001	3	6
BRCA	SEC23A →	+0.583	+0.451	<.001	<.001	3	5
BRCA	CORO1C →	+0.442	+0.485	<.001	<.001	3	5
HNSC	RLF →	+0.584	+0.426	.007	<.001	3	5
BRCA	GNL2 →	+0.616	+0.532	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 9,634 associations by consensus.

JUN vs SLC2A1 — HNSC

Explore this scatter interactively →