JUN

Across TCGA cell cohorts, JUN RNA expression is significantly associated with the go_rna of many other GO terms, with 5,170 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible JUN-associated GO terms across cancer lineages are Transforming growth factor beta1 production, Latent virus replication, and Release from viral latency. Each is linked with JUN in more than 16 cancer types. Because this analysis shows association rather than direction, both JUN-to-partner and partner-to-JUN results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Transforming growth factor beta1 production grouped by JUN-low versus JUN-high in SOFT_TISSUE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (JUN→partner) and Y-score (partner→JUN) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SOFT_TISSUE	Transforming growth factor beta1 production →	+0.351	+2.362	<.001	<.001	3	17
BONE	Latent virus replication →	+0.187	+2.558	<.001	<.001	3	16
BONE	Release from viral latency →	+0.187	+2.558	<.001	<.001	3	16
LUNG_SCLC	Cellular response to anisomycin →	+0.193	+1.418	<.001	<.001	3	16
BONE	SMAD protein signal transduction →	+0.222	+2.893	<.001	<.001	3	14
BONE	Integrated stress response signaling →	+0.169	+2.995	<.001	<.001	3	14

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,170 associations by consensus.

Transforming growth factor beta1 production by JUN expression — SOFT_TISSUE

Explore this box plot interactively →