JSRP1

Across TCGA cell cohorts, JSRP1 mutation is significantly associated with the RNA expression of many other genes, with 18 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible JSRP1-associated genes across cancer lineages are CLEC4F, GSTA3, and UNC79. Each is linked with JSRP1 in more than 1 cancer types. Because this analysis shows association rather than direction, both JSRP1-to-partner and partner-to-JSRP1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, CLEC4F grouped by JSRP1-low versus JSRP1-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (JSRP1→partner) and Y-score (partner→JSRP1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	CLEC4F →	+0.270	+3.974	<.001	.002	3	2
BLOOD_Leukemia	GSTA3 →	+0.017	+4.384	<.001	.006	3	2
LARGE_INTESTINE	UNC79 →	+0.218	+3.554	<.001	.007	3	1
LARGE_INTESTINE	CCDC54 →	+0.133	+3.736	<.001	.004	3	1
LARGE_INTESTINE	PDILT →	+0.006	+4.022	<.001	.006	3	1
LARGE_INTESTINE	ZNF454 →	+0.325	+3.658	<.001	.005	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 18 associations by consensus.

CLEC4F by JSRP1 expression — LARGE_INTESTINE

Explore this box plot interactively →