Across TCGA patient cohorts, JRKL RNA expression is significantly associated with the protein abundance of many other proteins, with 9,660 significant associations in total. PDAC shows the largest number of these associations.

The most reproducible JRKL-associated proteins across cancer lineages are MRE11, CCDC82_S131, and FAM76B_S193. Each is linked with JRKL in more than 5 cancer types. Because this analysis shows association rather than direction, both JRKL-to-partner and partner-to-JRKL results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (JRKL→partner) and Y-score (partner→JRKL) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	MRE11 →	+0.297	+0.450	.001	.001	3	6
BRCA	CCDC82_S131 →	+0.693	+0.684	<.001	<.001	3	5
LSCC	FAM76B_S193 →	+0.590	+0.727	<.001	<.001	3	5
HNSC	MTMR2 →	+0.314	+0.654	<.001	<.001	3	5
BRCA	MAML2 →	+0.400	+1.002	.001	<.001	3	4
HNSC	RAD50 →	+0.436	+0.488	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 9,660 associations by consensus.

Exploration

JRKL survival (RNA) · tumor vs normal (RNA) · all JRKL data types