JRK

Across TCGA cell cohorts, JRK RNA expression is significantly associated with the go_rna of many other GO terms, with 3,933 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible JRK-associated GO terms across cancer lineages are miRNA-mediated gene silencing by mRNA destabilization, Chromosome condensation, and Cilium or flagellum-dependent cell motility. Each is linked with JRK in more than 11 cancer types. Because this analysis shows association rather than direction, both JRK-to-partner and partner-to-JRK results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, miRNA-mediated gene silencing by mRNA destabilization grouped by JRK-low versus JRK-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (JRK→partner) and Y-score (partner→JRK) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	miRNA-mediated gene silencing by mRNA destabilization →	+0.179	+1.450	<.001	<.001	3	12
BONE	Chromosome condensation →	+0.166	+1.143	.003	.005	3	11
UPPER_AERODIGESTIVE_TRACT	Cilium or flagellum-dependent cell motility →	-0.089	-0.820	<.001	<.001	3	10
BONE	Pre-mRNA catabolic process →	+0.193	+1.117	<.001	<.001	3	10
UPPER_AERODIGESTIVE_TRACT	Flagellated sperm motility →	-0.089	-0.866	<.001	<.001	3	10
LARGE_INTESTINE	Regulation of centriole-centriole cohesion →	+0.133	+0.948	<.001	<.001	2	11

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,933 associations by consensus.

miRNA-mediated gene silencing by mRNA destabilization by JRK expression — BONE

Explore this box plot interactively →