JPH4

Across TCGA cell cohorts, JPH4 mutation is significantly associated with the RNA expression of many other genes, with 34 significant associations in total. STOMACH shows the largest number of these associations.

The most reproducible JPH4-associated genes across cancer lineages are OR2V2, PRAMEF20, and SOX1. Each is linked with JPH4 in more than 1 cancer types. Because this analysis shows association rather than direction, both JPH4-to-partner and partner-to-JPH4 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, OR2V2 grouped by JPH4-low versus JPH4-high in LUNG_NSCLC_LUAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (JPH4→partner) and Y-score (partner→JPH4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUAD	OR2V2 →	+0.020	+2.637	<.001	.007	3	2
LARGE_INTESTINE	PRAMEF20 →	+0.010	+4.022	<.001	.006	3	2
OVARY	SOX1 →	+0.581	+3.592	.005	.006	3	2
SKIN	MMP26 →	+0.020	+5.022	<.001	.002	3	1
SKIN	RESP18 →	+0.029	+4.415	<.001	.007	3	1
LUNG_NSCLC_LUAD	PTH2 →	+0.104	+2.803	<.001	.003	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 34 associations by consensus.

OR2V2 by JPH4 expression — LUNG_NSCLC_LUAD

Explore this box plot interactively →