JOSD2

Across TCGA patient cohorts, JOSD2 protein abundance is significantly associated with the RNA expression of many other genes, with 4,219 significant associations in total. GBM shows the largest number of these associations.

The most reproducible JOSD2-associated genes across cancer lineages are POM121L9P, PPP4R3A, and IDS. Each is linked with JOSD2 in more than 3 cancer types. Because this analysis shows association rather than direction, both JOSD2-to-partner and partner-to-JOSD2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, JOSD2 versus POM121L9P in GBM, with a Pearson correlation of 0.29.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (JOSD2→partner) and Y-score (partner→JOSD2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	POM121L9P →	+0.791	+0.440	.003	.001	3	4
LSCC	PPP4R3A →	-0.461	-0.286	<.001	.007	3	3
LUAD	IDS →	+0.531	+0.262	.003	.001	3	3
LSCC	PARP2 →	-0.550	-0.313	<.001	.003	3	3
GBM	CTSB →	+0.784	+0.364	<.001	.001	3	3
GBM	SLC37A2 →	+0.903	+0.563	.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,219 associations by consensus.

JOSD2 vs POM121L9P — GBM

Explore this scatter interactively →