JOSD2

Across TCGA cell cohorts, JOSD2 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,655 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible JOSD2-associated GO terms across cancer lineages are Retrograde transport, endosome to Golgi, Negative regulation of hyaluronan biosynthetic process, and Endocytic recycling. Each is linked with JOSD2 in more than 11 cancer types. Because this analysis shows association rather than direction, both JOSD2-to-partner and partner-to-JOSD2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Retrograde transport, endosome to Golgi grouped by JOSD2-low versus JOSD2-high in BREAST.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (JOSD2→partner) and Y-score (partner→JOSD2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BREAST	Retrograde transport, endosome to Golgi →	+0.077	+1.235	<.001	<.001	3	12
UPPER_AERODIGESTIVE_TRACT	Negative regulation of hyaluronan biosynthetic process →	+0.201	+1.354	.002	.004	3	11
UPPER_AERODIGESTIVE_TRACT	Endocytic recycling →	+0.063	+1.222	<.001	<.001	3	11
BONE	Negative regulation of protein-containing complex assembly →	+0.091	+1.229	.001	<.001	3	11
LUNG_NSCLC_LUSC	Negative regulation of inflammasome-mediated signaling pathway →	+0.165	+1.093	<.001	<.001	3	11
LUNG_NSCLC_LUSC	Negative regulation of NLRP3 inflammasome complex assembly →	+0.140	+0.994	<.001	<.001	3	11

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,655 associations by consensus.

Retrograde transport, endosome to Golgi by JOSD2 expression — BREAST

Explore this box plot interactively →