JMJD8

Across TCGA patient cohorts, JMJD8 protein abundance is significantly associated with the RNA expression of many other genes, with 3,379 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible JMJD8-associated genes across cancer lineages are CLCN3, CIB3, and NAV2. Each is linked with JMJD8 in more than 1 cancer types. Because this analysis shows association rather than direction, both JMJD8-to-partner and partner-to-JMJD8 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, JMJD8 versus CLCN3 in BRCA, with a Pearson correlation of 0.30.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (JMJD8→partner) and Y-score (partner→JMJD8) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	CLCN3 →	+0.633	+0.469	.007	.001	3	2
HNSC	CIB3 →	-0.365	-0.496	.005	<.001	3	2
GBM	NAV2 →	+0.658	+0.644	.007	.004	3	2
HNSC	RPL5P35 →	-0.266	-0.433	.005	.001	3	2
HNSC	RNU6-603P →	-1.596	-0.595	<.001	<.001	3	2
HNSC	RNU6-1223P →	-0.945	-0.574	.008	.006	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,379 associations by consensus.

JMJD8 vs CLCN3 — BRCA

Explore this scatter interactively →