JMJD7

Across TCGA patient cohorts, JMJD7 mutation is significantly associated with the immune_cell of many other genes, with 5 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible JMJD7-associated genes across cancer lineages are Monocytes, HSC, and lymphatic Endothelial cells. Each is linked with JMJD7 in more than 1 cancer types. Because this analysis shows association rather than direction, both JMJD7-to-partner and partner-to-JMJD7 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Monocytes grouped by JMJD7-low versus JMJD7-high in SKCM.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (JMJD7→partner) and Y-score (partner→JMJD7) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	Monocytes →	+0.024	+6.810	<.001	.017	3	1
UCEC	HSC →	+0.148	+2.178	.003	.035	3	1
UCEC	lymphatic Endothelial cells →	-0.024	-3.138	.026	.019	3	1
UCEC	pDC →	+0.076	+3.202	<.001	.009	3	1
UCEC	Astrocytes →	-0.044	-3.023	.039	.012	1	1

Each partner links to its Q-omics profile. Showing the 5 strongest of 5 associations by consensus.

Monocytes by JMJD7 expression — SKCM

Explore this box plot interactively →