JMJD6

Across TCGA patient cohorts, JMJD6 mutation is significantly associated with the RNA expression of many other genes, with 1,047 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible JMJD6-associated genes across cancer lineages are RN7SL248P, MIR7702, and NFYCP1. Each is linked with JMJD6 in more than 1 cancer types. Because this analysis shows association rather than direction, both JMJD6-to-partner and partner-to-JMJD6 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RN7SL248P grouped by JMJD6-low versus JMJD6-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (JMJD6→partner) and Y-score (partner→JMJD6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	RN7SL248P →	+0.059	+3.137	<.001	.005	3	2
UCEC	MIR7702 →	+0.171	+3.812	<.001	.008	3	2
CESC	NFYCP1 →	+0.036	+5.837	<.001	.001	3	2
UCEC	SLCO1B1 →	+0.183	+1.638	.003	.009	3	2
COAD	MIR425 →	+0.880	+3.437	<.001	.006	3	2
UCEC	SEPTIN14P24 →	+0.134	+2.534	.005	.006	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,047 associations by consensus.

RN7SL248P by JMJD6 expression — UCEC

Explore this box plot interactively →