JKAMP

Across TCGA patient cohorts, JKAMP mutation is significantly associated with the RNA expression of many other genes, with 773 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible JKAMP-associated genes across cancer lineages are RN7SKP128, RNU6-180P, and RN7SL314P. Each is linked with JKAMP in more than 2 cancer types. Because this analysis shows association rather than direction, both JKAMP-to-partner and partner-to-JKAMP results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RN7SKP128 grouped by JKAMP-low versus JKAMP-high in SKCM.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (JKAMP→partner) and Y-score (partner→JKAMP) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	RN7SKP128 →	+0.080	+5.408	<.001	.002	3	3
BLCA	RNU6-180P →	+0.356	+7.640	<.001	.009	3	2
LIHC	RN7SL314P →	+0.149	+4.878	<.001	.005	3	2
LIHC	MIR2278 →	+0.362	+4.647	.001	.007	3	2
CESC	RNA5SP351 →	+0.368	+5.424	<.001	<.001	3	2
CESC	LINC02402 →	+0.025	+4.969	<.001	.004	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 773 associations by consensus.

RN7SKP128 by JKAMP expression — SKCM

Explore this box plot interactively →