JAZF1-AS1

Across TCGA pan-cancer cohorts, JAZF1-AS1 RNA is linked to patient survival in 22 of 34 cancer types, making it the most broadly survival-associated JAZF1-AS1 data layer.

The strongest signal is observed in kidney renal papillary cell carcinoma (KIRP), where higher JAZF1-AS1 RNA is associated with worse overall survival. In most high-consensus cancer types, elevated JAZF1-AS1 expression acts as an unfavorable survival marker, although some lineages such as PAAD and CESC show a favorable association.

KIRP, PAAD, and CESC are the cancer types where JAZF1-AS1 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
KIRP	OS	Median	All	0.519	0.783	<.001	49	view →
PAAD	OS	Quartile	All	0.748	0.310	<.001	45	view →
CESC	OS	Quartile	II,III,IV	0.931	0.627	.002	38	view →
ACC	OS	Tertile	IV	0.968	0.374	.001	35	view →
UVM	DFS	Median	All	0.389	0.723	.003	19	view →
STAD	DFS	Quartile	All	0.480	0.626	.014	14	view →
THCA	DFS	Median	All	0.967	0.903	.003	13	view →
LUAD	DFS	Tertile	III,IV	0.463	0.828	.001	13	view →
LUSC	DFS	Tertile	All	0.859	0.592	.003	12	view →
COAD	OS	Tertile	IV	1.000	0.352	.016	10	view →
KIRC	DFS	Median	IV	0.284	0.602	.003	10	view →
SARC	OS	Tertile	All	0.750	0.495	.016	10	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 22 lineages.

JAZF1-AS1–KIRP (OS)

Open the KIRP breakdown →