JAZF1-AS1

Across TCGA pan-cancer cohorts, JAZF1-AS1 RNA differs between tumor and matched normal tissue in 14 of 18 cancer types tested, making tumor–normal expression one of JAZF1-AS1’s most consistent transcriptional readouts.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where JAZF1-AS1 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types JAZF1-AS1 is over-expressed in tumor, although a few such as BLCA and COAD show the opposite, repressed pattern.

KIRC, BLCA, and COAD are the cancer types where JAZF1-AS1 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in JAZF1-AS1 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
KIRC	Female	All	+0.139	<.001	9	view →
BLCA	Male	III,IV	−0.820	<.001	8	view →
COAD	Male	II,III,IV	−0.222	<.001	8	view →
LUSC	Female	II,III,IV	−0.199	<.001	8	view →
LUAD	Female	III,IV	−0.180	<.001	7	view →
UCEC	All	III,IV	−0.865	<.001	6	view →
BRCA	All	II,III,IV	−0.171	<.001	6	view →
STAD	All	All	−0.163	.004	5	view →
LIHC	All	All	+0.088	.002	5	view →
READ	All	All	−0.393	.003	3	view →
KICH	All	All	−0.067	.006	3	view →
PRAD	All	All	−0.508	<.001	2	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 12 strongest of 14 lineages.

JAZF1-AS1–KIRC

Open the KIRC breakdown →