JAKMIP3

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, JAKMIP3 mutation is significantly associated with the RNA expression of many other genes, with 3,392 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible JAKMIP3-associated genes across cancer lineages are TIMM44, TTL, and MRPS15. Each is linked with JAKMIP3 in more than 2 cancer types. Because this analysis shows association rather than direction, both JAKMIP3-to-partner and partner-to-JAKMIP3 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (JAKMIP3→partner) and Y-score (partner→JAKMIP3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
UCECTIMM44 →+0.302+2.295.002<.00133
UCECTTL →+0.341+1.473.002.00733
UCECMRPS15 →+0.346+4.212.001<.00133
LUADRNU6-225P →+0.412+6.924<.001<.00133
SKCMMRPL22 →+0.391+2.944<.001<.00133
UCECRN7SL163P →+0.114+1.501<.001.00633
Each partner links to its Q-omics profile. Showing the 6 strongest of 3,392 associations by consensus.

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