JAKMIP2-AS1

Across TCGA patient cohorts, JAKMIP2-AS1 RNA expression is significantly associated with the go_rna of many other GO terms, with 7,045 significant associations in total. STAD shows the largest number of these associations.

The most reproducible JAKMIP2-AS1-associated GO terms across cancer lineages are Smoothened signaling pathway, Regulation of microtubule polymerization or depolymerization, and Positive regulation of epithelial to mesenchymal transition. Each is linked with JAKMIP2-AS1 in more than 16 cancer types. Because this analysis shows association rather than direction, both JAKMIP2-AS1-to-partner and partner-to-JAKMIP2-AS1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Smoothened signaling pathway grouped by JAKMIP2-AS1-low versus JAKMIP2-AS1-high in ESCA.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (JAKMIP2-AS1→partner) and Y-score (partner→JAKMIP2-AS1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
ESCA	Smoothened signaling pathway →	+0.052	+0.134	<.001	<.001	3	17
ESCA	Regulation of microtubule polymerization or depolymerization →	+0.059	+0.115	<.001	<.001	3	17
TGCT	Positive regulation of epithelial to mesenchymal transition →	+0.071	+0.856	<.001	<.001	3	16
STAD	Positive regulation of proteolysis involved in protein catabolic process →	+0.067	+0.084	<.001	<.001	3	16
TGCT	Regulation of animal organ morphogenesis →	+0.064	+0.895	<.001	<.001	3	16
STAD	Regulation of microtubule cytoskeleton organization →	+0.060	+0.075	<.001	<.001	3	16

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,045 associations by consensus.

Smoothened signaling pathway by JAKMIP2-AS1 expression — ESCA

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