JAKMIP1

Across TCGA cell cohorts, JAKMIP1 mutation is significantly associated with the mutation status of many other genes, with 7,443 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible JAKMIP1-associated genes across cancer lineages are BICRA, TNRC6A, and SCUBE1. Each is linked with JAKMIP1 in more than 6 cancer types. Because this analysis shows association rather than direction, both JAKMIP1-to-partner and partner-to-JAKMIP1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, BICRA grouped by JAKMIP1-low versus JAKMIP1-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (JAKMIP1→partner) and Y-score (partner→JAKMIP1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	BICRA →	+3.278	+3.070	<.001	<.001	1	7
OVARY	TNRC6A →	+3.684	+3.217	.006	.006	1	5
UPPER_AERODIGESTIVE_TRACT	SCUBE1 →	+5.392	+5.392	.004	.004	1	5
LUNG_SCLC	TENM1 →	+2.263	+3.900	.006	.006	1	5
OVARY	TECTA →	+2.514	+4.378	<.001	<.001	1	5
BLOOD_Lymphoma	PLXNA1 →	+3.731	+3.938	<.001	<.001	1	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,443 associations by consensus.

BICRA by JAKMIP1 expression — LARGE_INTESTINE

Explore this box plot interactively →