Across TCGA patient cohorts, JAG2 RNA expression is significantly associated with the protein abundance of many other proteins, with 14,367 significant associations in total. LUAD shows the largest number of these associations.

The most reproducible JAG2-associated proteins across cancer lineages are GCC2, NUDT14, and COPG1. Each is linked with JAG2 in more than 4 cancer types. Because this analysis shows association rather than direction, both JAG2-to-partner and partner-to-JAG2 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (JAG2→partner) and Y-score (partner→JAG2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	GCC2 →	-0.278	-0.911	<.001	<.001	3	5
LSCC	NUDT14 →	+0.355	+0.550	<.001	.005	3	4
LSCC	COPG1 →	-0.197	-0.772	.001	<.001	3	4
LSCC	FRMD6_S544 →	+0.910	+0.945	<.001	<.001	3	4
OV	SEC23B →	-0.338	-1.046	.003	.003	2	5
LUAD	SNX5 →	-0.245	-0.931	<.001	.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 14,367 associations by consensus.

Exploration

JAG2 survival (RNA) · tumor vs normal (RNA) · all JAG2 data types