Across TCGA cell cohorts, JAG2 mutation is significantly associated with the RNA expression of many other genes, with 949 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible JAG2-associated genes across cancer lineages are OR4F4, TPPP2, and DAZ2. Each is linked with JAG2 in more than 2 cancer types. Because this analysis shows association rather than direction, both JAG2-to-partner and partner-to-JAG2 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (JAG2→partner) and Y-score (partner→JAG2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Lymphoma	OR4F4 →	+0.006	+3.169	.006	.008	3	3
KIDNEY	TPPP2 →	+0.043	+5.000	<.001	.005	3	2
KIDNEY	DAZ2 →	+0.013	+5.000	<.001	.005	3	2
KIDNEY	PRR23C →	+0.006	+5.000	<.001	.005	3	2
CNS	CFAP100 →	+0.074	+2.514	.009	.007	3	2
BLOOD_Leukemia	FLG2 →	+0.077	+3.100	<.001	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 949 associations by consensus.

Exploration

JAG2 survival (RNA) · tumor vs normal (RNA) · all JAG2 data types