IZUMO1R

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, IZUMO1R mutation is significantly associated with the RNA expression of many other genes, with 257 significant associations in total. SKCM shows the largest number of these associations.

The most reproducible IZUMO1R-associated genes across cancer lineages are MIR941-4, BTF3P15, and MIR4441. Each is linked with IZUMO1R in more than 1 cancer types. Because this analysis shows association rather than direction, both IZUMO1R-to-partner and partner-to-IZUMO1R results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (IZUMO1R→partner) and Y-score (partner→IZUMO1R) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
UCECMIR941-4 →+0.976+4.302<.001.00232
UCECBTF3P15 →+0.181+4.538<.001.00632
SKCMMIR4441 →+0.119+3.900<.001.00832
SKCMRNU6-1255P →+0.277+2.628<.001.00132
BRCALINC02281 →+0.122+6.215<.001.00131
BRCARNU1-154P →+0.359+5.347<.001.00631
Each partner links to its Q-omics profile. Showing the 6 strongest of 257 associations by consensus.

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