Across TCGA cell cohorts, IZUMO1R RNA expression is significantly associated with the go_rna of many other GO terms, with 715 significant associations in total. SKIN shows the largest number of these associations.

The most reproducible IZUMO1R-associated GO terms across cancer lineages are Cellular response to cell-matrix adhesion, Cellular response to oxygen levels, and Regulation of metaphase/anaphase transition of meiotic cell cycle. Each is linked with IZUMO1R in more than 3 cancer types. Because this analysis shows association rather than direction, both IZUMO1R-to-partner and partner-to-IZUMO1R results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (IZUMO1R→partner) and Y-score (partner→IZUMO1R) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKIN	Cellular response to cell-matrix adhesion →	+0.213	+0.127	<.001	<.001	3	4
SKIN	Cellular response to oxygen levels →	+0.027	+0.111	.008	<.001	3	4
LUNG_NSCLC_LUSC	Regulation of metaphase/anaphase transition of meiotic cell cycle →	-0.148	-0.054	<.001	.009	3	3
LUNG_NSCLC_LUSC	Regulation of meiotic chromosome separation →	-0.148	-0.054	<.001	.009	3	3
KIDNEY	Leukocyte apoptotic process →	+0.116	+0.061	.001	.003	3	3
KIDNEY	B cell apoptotic process →	+0.159	+0.050	.006	.006	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 715 associations by consensus.

Exploration

IZUMO1R survival (RNA) · tumor vs normal (RNA) · all IZUMO1R data types