IZUMO1

Across TCGA patient cohorts, IZUMO1 RNA expression is significantly associated with the protein abundance of many other proteins, with 12,553 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible IZUMO1-associated proteins across cancer lineages are GALNT2, MCAM, and COG1. Each is linked with IZUMO1 in more than 4 cancer types. Because this analysis shows association rather than direction, both IZUMO1-to-partner and partner-to-IZUMO1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, IZUMO1 versus GALNT2 in CCRCC, with a Pearson correlation of -0.30.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (IZUMO1→partner) and Y-score (partner→IZUMO1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CCRCC	GALNT2 →	-0.370	-0.316	.004	<.001	3	5
CCRCC	MCAM →	+0.506	+0.338	<.001	<.001	3	5
UCEC	COG1 →	-0.238	-0.549	<.001	.001	3	4
UCEC	KCTD15_S38 →	+0.646	+0.408	<.001	.006	3	4
CCRCC	ACBD3 →	-0.200	-0.295	.002	.001	3	4
OV	TMED9 →	-0.326	-0.236	.005	.005	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 12,553 associations by consensus.

IZUMO1 vs GALNT2 — CCRCC

Explore this scatter interactively →