IYD

Across TCGA patient cohorts, IYD RNA expression is significantly associated with the protein abundance of many other proteins, with 12,207 significant associations in total. LUAD shows the largest number of these associations.

The most reproducible IYD-associated proteins across cancer lineages are SH3BGRL2, TSPAN1, and VWA5A. Each is linked with IYD in more than 5 cancer types. Because this analysis shows association rather than direction, both IYD-to-partner and partner-to-IYD results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, IYD versus SH3BGRL2 in LUAD, with a Pearson correlation of 0.46.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (IYD→partner) and Y-score (partner→IYD) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	SH3BGRL2 →	+0.471	+1.547	<.001	<.001	3	6
UCEC	TSPAN1 →	+1.055	+0.623	.002	.009	3	5
BRCA	VWA5A →	+0.642	+1.123	<.001	<.001	3	5
UCEC	PLS1 →	+0.478	+0.458	<.001	.005	3	5
BRCA	MDC1 →	-0.414	-0.992	<.001	<.001	3	5
BRCA	CAB39L →	+0.537	+0.833	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 12,207 associations by consensus.

IYD vs SH3BGRL2 — LUAD

Explore this scatter interactively →